Table 9

Here are the column names of the data we are plotting:

fouraminobutyrate, glutarate, lysine and pyruvate represent different parts of the butyrate synthesis pathway.

HR	Lower_CI	Upper_CI	pvalue	modelname	source	type
0.71	0.52	0.97	0.030	log(ACoA)	external melanoma	pfs
0.81	0.62	1.06	0.117	log(Ruminococcaceae)	external melanoma	pfs
0.67	0.43	1.04	0.072	log(Ruminococcacaeae + Lachnospiraceae)	external melanoma	pfs
0.64	0.39	1.03	0.064	log(Clostridiales)	external melanoma	pfs
0.70	0.45	1.09	0.112	log(Clostridia)	external melanoma	pfs
0.97	0.93	1.01	0.134	log(F prausnitizii + 1e-7)	external melanoma	pfs

Univariate Cox regression analyses PFS relationship to ACoA gene abundance in MSK Observational Data.

HR	Lower_CI	Upper_CI	pvalue	modelname	source	type
0.59	0.38	0.90	0.015	log(ACoA)	mixed solid tumor	pfs
1.03	0.79	1.35	0.825	log(Ruminococcaceae)	mixed solid tumor	pfs
0.77	0.46	1.28	0.316	log(Ruminococcacaeae + Lachnospiraceae)	mixed solid tumor	pfs
0.79	0.46	1.36	0.391	log(Clostridiales)	mixed solid tumor	pfs
0.83	0.49	1.41	0.488	log(Clostridia)	mixed solid tumor	pfs
0.99	0.94	1.05	0.764	log(F prausnitizii + 1e-7)	mixed solid tumor	pfs

HR	Lower_CI	Upper_CI	pvalue	modelname	source	type
0.40	0.24	0.66	0.000	log(ACoA)	mixed solid tumor	os
0.96	0.71	1.29	0.774	log(Ruminococcaceae)	mixed solid tumor	os
0.45	0.25	0.81	0.008	log(Ruminococcacaeae + Lachnospiraceae)	mixed solid tumor	os
0.43	0.23	0.80	0.008	log(Clostridiales)	mixed solid tumor	os
0.58	0.31	1.06	0.076	log(Clostridia)	mixed solid tumor	os
0.95	0.89	1.01	0.126	log(F prausnitizii + 1e-7)	mixed solid tumor	os